Description

5-Bromo-2-Mercaptoquinazolin-4(3H)-One is a high-value brominated quinazolinone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and mercapto functional groups, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating specialized organic ligands, dyes, and photoactive compounds.
• Chemical Biology: Useful as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & R&D: Serves as a standard or starting material in university and industrial research laboratories for novel synthetic methodologies.

Basic Information

Product Name	5-Bromo-2-Mercaptoquinazolin-4(3H)-One
CAS No.	2231674-69-2
Molecular Formula	C8H5BrN2OS
Molecular Weight	257.11 g/mol
Synonyms	5-Bromo-2-mercapto-3,4-dihydro-4-oxoquinazoline; 5-Bromo-2-thioxo-1,2-dihydroquinazolin-4(3H)-one; 4(3H)-Quinazolinone, 5-bromo-2-mercapto-; 5-Bromo-2-sulfanyl-3H-quinazolin-4-one; 5-Bromo-2-mercapto-4(3H)-quinazolinone; 5-Bromo-2-thioquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Mercaptoquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.