Description

Methyl 6-tert-Butylthieno[3,2-D]Pyrimidine-4-Carboxylate CAS NO 2231673-05-3 is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with targeted biological activity. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitor candidates targeting oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic systems in organic and process chemistry.
• Biochemical Tool Compound: May be utilized in the development of biochemical probes for studying specific enzymatic pathways and cellular mechanisms.

Basic Information

Product Name	Methyl 6-tert-Butylthieno[3,2-D]Pyrimidine-4-Carboxylate
CAS No.	2231673-05-3
Molecular Formula	C12H14N2O2S
Molecular Weight	250.32 g/mol
Synonyms	Methyl 6-(tert-butyl)thieno[3,2-d]pyrimidine-4-carboxylate; 6-tert-Butylthieno[3,2-d]pyrimidine-4-carboxylic acid methyl ester; Thieno[3,2-d]pyrimidine-4-carboxylic acid, 6-(1,1-dimethylethyl)-, methyl ester; Methyl 6-tert-butylthieno[3,2-d]pyrimidine-4-carboxylate; 2231673-05-3
EINECS	Contact for details

Quality Control

Our Methyl 6-tert-Butylthieno[3,2-D]Pyrimidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.