Description

2-Quinazolinamine, 7-Bromo-n-(1,3-Dimethyl-1H-Pyrazol-4-Yl)- is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists seeking to develop novel therapeutic agents, particularly in oncology and other disease areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel quinazoline-based drug candidates.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for targeted cancer therapies.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed as a reference standard or probe in biochemical assays to study specific biological pathways.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of active pharmaceutical ingredients (APIs) in clinical trials.
• Academic Research: Used in university laboratories for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	2-Quinazolinamine, 7-Bromo-n-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-
CAS No.	2227206-75-7
Molecular Formula	C₁₃H₁₂BrN₅
Molecular Weight	318.18 g/mol
Synonyms	7-Bromo-N-(1,3-dimethyl-1H-pyrazol-4-yl)quinazolin-2-amine; 7-Bromo-N-(1,3-dimethylpyrazol-4-yl)quinazolin-2-amine; 2-Amino-7-bromo-N-(1,3-dimethyl-1H-pyrazol-4-yl)quinazoline; 2227206-75-7; 7-Bromo-2-((1,3-dimethyl-1H-pyrazol-4-yl)amino)quinazoline; BDBM50164955; AKOS026713194; ZINC000253907952
EINECS	Contact for details

Quality Control

Our 2-Quinazolinamine, 7-Bromo-n-(1,3-Dimethyl-1H-Pyrazol-4-Yl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system supports the needs of clients operating under cGMP, ISO, or other rigorous regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.