Description

2-(Ethoxy)Pyrimidine-5-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of pyrimidine-based drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used to construct novel heterocyclic compounds for crop protection and pesticide development.
• Material Science: Serves as a precursor for creating functional organic molecules used in electronic materials and OLEDs.
• Chemical Synthesis: Enables precise, palladium-catalyzed cross-coupling to introduce the 2-ethoxypyrimidine moiety into complex molecular architectures.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-(Ethoxy)Pyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	2223035-77-4
Molecular Formula	C₁₂H₁₉BN₂O₃
Molecular Weight	250.10 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethoxypyrimidine; 2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Ethoxypyrimidine-5-boronic acid pinacol ester; 5-Borono-2-ethoxypyrimidine pinacol ester; Pyrimidine, 2-ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Every batch of 2-(Ethoxy)Pyrimidine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management protocols. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical characterization including NMR and HPLC. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.