Description

2-Chloro-4-(Difluoromethoxy)Benzaldehyde is a high-purity aromatic aldehyde building block characterized by its chloro and difluoromethoxy substituents. This compound is a critical intermediate in advanced organic synthesis, valued for its ability to introduce specific halogenated and fluorinated motifs into target molecules. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Organic Electronic Materials: Intermediate for creating specialized monomers and polymers used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial research in organic chemistry, medicinal chemistry, and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	2-Chloro-4-(Difluoromethoxy)Benzaldehyde
CAS No.	2222644-34-8
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	2-Chloro-4-(difluoromethoxy)benzaldehyde; 4-(Difluoromethoxy)-2-chlorobenzaldehyde; Benzaldehyde, 2-chloro-4-(difluoromethoxy)-; 2-Chloro-α-formyl-4-(difluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(Difluoromethoxy)Benzaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.