Description

Fmoc-Glu(Otbu)-Glu(Otbu)-Nh2 is a protected dipeptide building block, specifically designed for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected dipeptide fragment for the efficient, sequential assembly of longer peptide chains.
• Pharmaceutical Research: Intermediate in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used to introduce specific glutamic acid sequences into proteins, antibodies, or other biomolecules for labeling or functionalization.
• Biochemical Tool Development: Synthesis of substrates, inhibitors, or probes for enzyme studies and diagnostic assays.
• Combinatorial Chemistry: Building block in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Contract Research: Essential reagent for fundamental peptide chemistry research and custom synthesis services.

Basic Information

Product Name	Fmoc-Glu(Otbu)-Glu(Otbu)-Nh2
CAS No.	2222252-86-8
Molecular Formula	C34H45N3O9
Molecular Weight	639.74 g/mol
Synonyms	Fmoc-Glu(OtBu)-Glu(OtBu)-NH2; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic acid 1-(1,1-dimethylethyl) ester 5-(1,1-dimethylethyl) ester; Fmoc-Glu(OtBu)-Glu(OtBu)-amide; Fmoc-Glu(OtBu)-Glu(OtBu)-NH2; Fmoc-L-Glu(OtBu)-L-Glu(OtBu)-NH2; Fmoc-Glu(OtBu)-Glu(OtBu) Amide; Protected Fmoc-Glutamyl-Glutamine Dipeptide; Fmoc-E(OtBu)-E(OtBu)-NH2
EINECS	Contact for details

Quality Control

Our Fmoc-Glu(Otbu)-Glu(Otbu)-Nh2 is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.