Description

(S)-2-Amino-3-Guanidinopropanoic Acid Dihydrochloride CAS NO 2216751-08-3 is a high-purity, non-natural amino acid derivative, specifically the dihydrochloride salt of L-arginine's enantiomer. This compound is a critical chiral building block and biochemical reagent for advanced research and pharmaceutical development. It is essential for scientists and manufacturers in the fields of peptide synthesis, medicinal chemistry, and biochemical research who require enantiomerically pure, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in peptide-based therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Peptide Synthesis: Serves as a protected or modified arginine analogue in solid-phase and solution-phase peptide synthesis to introduce specific functionalities or study structure-activity relationships.
• Medicinal Chemistry: Employed in the design and synthesis of drug candidates targeting processes involving arginine metabolism, nitric oxide synthase, or guanidino-group recognition.
• Reference Standard: Utilized as a high-purity certified reference material (CRM) for quality control and analytical testing in pharmaceutical and research laboratories.

Basic Information

Product Name	(S)-2-Amino-3-Guanidinopropanoic Acid Dihydrochloride
CAS No.	2216751-08-3
Molecular Formula	C4H12Cl2N4O2
Molecular Weight	219.07 g/mol
Synonyms	(S)-2-Amino-3-guanidinopropionic acid dihydrochloride; D-Arg HCl; D-Arginine dihydrochloride; (R)-2-Amino-5-guanidinopentanoic acid dihydrochloride (common misassignment, verify structure); (S)-2-Amino-3-[(diaminomethylidene)amino]propanoic acid dihydrochloride; D-Arg·2HCl; (S)-Amino-3-guanidinopropanoate dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-Guanidinopropanoic Acid Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. After opening, handle under an inert atmosphere or in a dry glovebox to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.