Description

1-Cyclopropyl-7-Fluoro-8-Methoxy-6-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a sophisticated scaffold for creating targeted drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antibiotics and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel fluoroquinolone antibiotic candidates and other complex bioactive molecules.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves as a critical precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) targeting bacterial infections.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying advanced heterocyclic chemistry and antimicrobial mechanisms.
• Process Chemistry Scale-up: Employed in the development and optimization of scalable, GMP-compliant synthetic routes for clinical trial material production.

Basic Information

Product Name	1-Cyclopropyl-7-Fluoro-8-Methoxy-6-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
CAS No.	2205053-60-5
Molecular Formula	C22H24FN3O4
Molecular Weight	413.45 g/mol
Synonyms	1-Cyclopropyl-7-fluoro-8-methoxy-6-((4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; (4aR,7aR)-6-(1-Cyclopropyl-7-fluoro-8-methoxy-4-oxo-1,4-dihydroquinolin-6-yl)octahydro-1H-pyrrolo[3,4-b]pyridine-3-carboxylic acid; Advanced Fluoroquinolone Intermediate; CAS 2205053-60-5; Octahydropyrrolopyridine-quinolone carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-7-Fluoro-8-Methoxy-6-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/UPLC) are provided for every shipment, confirming compliance with client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.