Description

1-(3-Fluorophenyl)But-3-Yn-2-Amine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is valued for its unique molecular scaffold, which incorporates both a fluorinated aromatic ring and an amine functional group, making it a versatile synthon in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorophenyl and alkyne-amine motifs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and pesticides.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeled compounds for biochemical assays and imaging.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and catalysis.
• Custom Synthesis Starting Material: A critical raw material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	1-(3-Fluorophenyl)But-3-Yn-2-Amine Hydrochloride
CAS No.	2193065-31-3
Molecular Formula	C10H11FN•HCl
Molecular Weight	199.66 g/mol (Free base)
Synonyms	1-(3-Fluorophenyl)-3-butyn-2-amine hydrochloride; 3-Fluoro-α-(1-propynyl)benzylamine hydrochloride; 1-(3-Fluorophenyl)but-3-yn-2-amine HCl; 2-Amino-1-(3-fluorophenyl)but-3-yne hydrochloride; But-3-yn-2-amine, 1-(3-fluorophenyl)-, hydrochloride; 3-Fluorophenylbutynylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)But-3-Yn-2-Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized by modern analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.