Description

5-Pyrimidinecarboxamide, 2-[5-[(3-Ethoxy-2-Pyridinyl)Oxy]-3-Pyridinyl]-n-[(3S)-Tetrahydro-3-Furanyl]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its complex pyrimidine and pyridine core structure.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), particularly in oncology and antiviral research.
• Biochemical Tool Compound: Employed in biochemical assays and as a probe to study specific enzyme interactions and biological mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	5-Pyrimidinecarboxamide, 2-[5-[(3-Ethoxy-2-Pyridinyl)Oxy]-3-Pyridinyl]-n-[(3S)-Tetrahydro-3-Furanyl]-
CAS No.	2186700-33-2
Molecular Formula	C21H23N5O4
Molecular Weight	409.44 g/mol
Synonyms	2-[5-[(3-Ethoxy-2-pyridinyl)oxy]-3-pyridinyl]-N-[(3S)-tetrahydro-3-furanyl]-5-pyrimidinecarboxamide; (3S)-N-(Tetrahydrofuran-3-yl)-2-[5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl]pyrimidine-5-carboxamide; UNII-6U9K6K3W1S; 6U9K6K3W1S; 2186700-33-2; 2-(5-((3-Ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-((S)-tetrahydrofuran-3-yl)pyrimidine-5-carboxamide; 2-[5-[(3-Ethoxy-2-pyridinyl)oxy]-3-pyridinyl]-N-[(3S)-oxolan-3-yl]pyrimidine-5-carboxamide
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxamide intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.