Description

Phenylalanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3-Phenoxy- is a specialized, protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks to construct complex peptides with specific structural features. It is primarily utilized in pharmaceutical R&D, particularly in the development of novel therapeutic peptides and peptidomimetics, where precise molecular architecture is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid building block for the sequential assembly of peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of peptide-based drug candidates targeting various diseases.
• Bioconjugation: Acts as a modified amino acid component for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry Libraries: Employed to generate diverse libraries of peptide analogs for high-throughput screening.
• Chemical Biology Probes: Incorporated into peptides used as tools to study protein function and biological pathways.
• Process Development: Used in scaling up the production of therapeutic peptides under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	Phenylalanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3-Phenoxy-
CAS No.	2171574-18-6
Molecular Formula	C31H25NO5
Molecular Weight	491.54 g/mol
Synonyms	Fmoc-3-phenoxy-L-phenylalanine; Fmoc-Phe(3-OPh)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-phenoxy-L-phenylalanine; N-α-Fmoc-O-3-phenyl-L-tyrosine; Fmoc-Tyr(3-OPh)-OH; Fmoc-O-3-phenyl-L-tyrosine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-[3-(phenoxy)phenyl]propanoic acid
EINECS	Contact for details

Quality Control

Our Phenylalanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3-Phenoxy- is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.