Description

Fmoc-Ala-Pro-Oh CAS NO 2171246-67-4 is a high-purity, protected dipeptide building block essential for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly in the development of complex biomolecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic institutions engaged in the synthesis of therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the sequential construction of custom peptide sequences.
• Pharmaceutical Research: Intermediate in the development and scale-up of novel therapeutic peptides targeting various diseases.
• Bioconjugation: Used to introduce specific Ala-Pro motifs into larger proteins or carrier molecules for drug delivery systems.
• Combinatorial Chemistry: A valuable building block for generating diverse peptide libraries for high-throughput screening.
• Biochemical Tool Development: Synthesis of enzyme substrates, inhibitors, or fluorescent probes for proteomics and enzymology studies.
• Academic Research: Fundamental studies in peptide structure, folding, and bioactivity.

Basic Information

Product Name	Fmoc-Ala-Pro-Oh
CAS No.	2171246-67-4
Molecular Formula	C23H24N2O5
Molecular Weight	408.45 g/mol
Synonyms	Fmoc-L-Ala-L-Pro-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-proline; Fmoc-Ala-Pro; Fmoc-Alanine-Proline; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid - (S)-pyrrolidine-2-carboxylic acid (1:1); Fmoc-Ala-Pro dipeptide; N-Fmoc-L-alanyl-L-proline; Fmoc-Ala-Pro-OH (Fmoc-L-Ala-L-Pro-OH)
EINECS	Contact for details

Quality Control

Our Fmoc-Ala-Pro-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices and can provide material traceable to relevant standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.