Description

Benzene, 4-Bromo-1-(Difluoromethyl)-2-(Trifluoromethoxy)- is a highly fluorinated and halogenated benzene derivative, representing a sophisticated building block for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining bromo, difluoromethyl, and trifluoromethoxy substituents to impart specific electronic and steric properties critical for modulating bioactivity and material characteristics. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly where fluorine substitution is used to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Active Ingredient Development: Used in research to create new herbicides, fungicides, and insecticides, leveraging the fluorine atoms for improved lipophilicity and environmental persistence.
• Advanced Material Synthesis: Acts as a monomer or functionalizing agent in the production of specialty polymers, coatings, and liquid crystals with tailored thermal, optical, or chemical resistance properties.
• Organic Electronic Materials: Investigated as a component in the development of organic light-emitting diodes (OLEDs) or semiconductors due to its potential charge-transport characteristics.
• Chemical Research & Development: Employed in academic and industrial R&D settings for methodological studies in cross-coupling reactions, fluorination chemistry, and the exploration of new chemical spaces.

Basic Information

Product Name	Benzene, 4-Bromo-1-(Difluoromethyl)-2-(Trifluoromethoxy)-
CAS No.	2167524-80-1
Molecular Formula	C8H4BrF5O
Molecular Weight	291.02 g/mol
Synonyms	4-Bromo-1-(difluoromethyl)-2-(trifluoromethoxy)benzene; 1-Bromo-4-(difluoromethyl)-2-(trifluoromethoxy)benzene; 2-(Trifluoromethoxy)-4-bromobenzylidene difluoride; 4-Bromo-α,α-difluoro-2-(trifluoromethoxy)toluene; 4-Bromo-2-(trifluoromethoxy)benzylidene difluoride; 2-(Trifluoromethoxy)-4-bromobenzaldehyde difluoride; Benzene, 1-bromo-4-(difluoromethyl)-2-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our Benzene, 4-Bromo-1-(Difluoromethyl)-2-(Trifluoromethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is likely moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.