Description

(S)-5-(Piperidin-3-Yl)Pyrimidine CAS NO 2165572-27-8 is a high-purity, chiral piperidine-pyrimidine hybrid compound that serves as a critical building block in modern pharmaceutical research and development. Its unique structure makes it a valuable intermediate for constructing complex molecules with specific biological activity. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Library Synthesis: Employed in the construction of diverse screening libraries for high-throughput screening (HTS) against novel biological targets.
• Process Chemistry: Serves as a starting material or advanced intermediate in the development of scalable, cost-effective synthetic routes for candidate drugs.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function, receptor binding, and other biochemical pathways.

Basic Information

Product Name	(S)-5-(Piperidin-3-Yl)Pyrimidine
CAS No.	2165572-27-8
Molecular Formula	C9H13N3
Molecular Weight	163.22 g/mol
Synonyms	(S)-5-(3-Piperidyl)pyrimidine; (S)-5-(Piperidin-3-yl)pyrimidine; (3S)-5-(3-Piperidinyl)pyrimidine; 5-[(3S)-Piperidin-3-yl]pyrimidine; (S)-3-(Pyrimidin-5-yl)piperidine; 2165572-27-8; (S)-5-(Piperidin-3-Yl)Pyrimidine
EINECS	Contact for details

Quality Control

Our (S)-5-(Piperidin-3-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.