Description

5,6-Difluoro-Benzooxazole-2-Thiol is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure containing both fluorine and sulfur. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents. Its specific substitution pattern makes it a valuable synthon for targeted molecular design.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the difluoro-benzooxazole scaffold can contribute to biological activity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand Synthesis: Utilized for constructing complex chelating ligands in coordination chemistry and catalysis.
• Fluorescent Probe Development: Acts as a core structure for synthesizing fluorophores and molecular sensors used in bioimaging and diagnostics.

Basic Information

Product Name	5,6-Difluoro-Benzooxazole-2-Thiol
CAS No.	2137825-38-6
Molecular Formula	C7H3F2NOS
Molecular Weight	187.17 g/mol
Synonyms	5,6-Difluoro-1,3-benzoxazole-2-thiol; 5,6-Difluoro-2-mercaptobenzoxazole; 2-Mercapto-5,6-difluorobenzoxazole; 5,6-Difluorobenzo[d]oxazole-2-thiol; Benzooxazole-2-thiol, 5,6-difluoro-; 2-Thiol-5,6-difluorobenzoxazole
EINECS	Contact for details

Quality Control

Every batch of 5,6-Difluoro-Benzooxazole-2-Thiol is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.