Description

Fmoc-Ser(Ipr)-Oh is a protected amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity building blocks to construct complex peptides with precise stereochemistry. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the development of therapeutic peptides, diagnostic agents, and biochemical probes. The isopropyl-protected serine side chain offers enhanced stability during the synthesis of challenging peptide sequences.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected building block for the automated synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including hormones, antibiotics, and enzyme inhibitors.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Bioconjugation: Acts as a precursor for creating peptide-drug conjugates or peptide-labeled biomolecules.
• Academic & Contract Research: Essential reagent for fundamental biochemical studies and for contract research organizations (CROs) providing peptide synthesis services.
• Process Development: Used in scaling up the production of peptide active pharmaceutical ingredients (APIs) under GMP-like conditions.

Basic Information

Product Name	Fmoc-Ser(Ipr)-Oh
CAS No.	2137146-08-6
Molecular Formula	C22H25NO5
Molecular Weight	383.44 g/mol
Synonyms	Fmoc-Ser(O-iPr)-OH; N-(9-Fluorenylmethoxycarbonyl)-O-isopropyl-L-serine; Fmoc-O-isopropyl-L-serine; Fmoc-L-Ser(O-iPr)-OH; (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(propan-2-yloxy)propanoic acid; Fmoc-Ser(Ipr)-OH; Fmoc-Ser(O-iPr)-OH; N-α-Fmoc-O-isopropyl-L-serine
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Ser(Ipr)-Oh is manufactured and tested to meet stringent quality standards suitable for advanced research and pharmaceutical applications. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity, correct stereochemistry, and batch-to-batch consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to a quality management system to support our commitment to reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.