Description

3-(2,4-Dimethyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)-Benzenamine is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl-substituted aniline core linked to a dimethylimidazole moiety. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity and metabolic stability. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to develop next-generation drugs in oncology, neurology, and anti-infective fields.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products, leveraging the stability of the trifluoromethyl group.
• Material Science: Serves as a precursor for functional polymers and advanced organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a probe or linker in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Industrial R&D: Essential for research in heterocyclic and fluorine chemistry, enabling the exploration of new chemical spaces.

Basic Information

Product Name	3-(2,4-Dimethyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)-Benzenamine
CAS No.	2119583-28-5
Molecular Formula	C12H12F3N3
Molecular Weight	255.24 g/mol
Synonyms	5-(Trifluoromethyl)-3-(2,4-dimethylimidazol-1-yl)aniline; 3-(2,4-Dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline; 1-[3-Amino-5-(trifluoromethyl)phenyl]-2,4-dimethyl-1H-imidazole; Benzenamine, 3-(2,4-dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-; 2119583-28-5
EINECS	Contact for details

Quality Control

Our 3-(2,4-Dimethyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)-Benzenamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.