Description

Ethyl 1H-Pyrazolo[3,4-D]Pyrimidine-6-Carboxylate is a high-purity heterocyclic building block of significant importance in modern synthetic chemistry. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of targeted therapeutics for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors for cancer therapy.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study specific biological pathways.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for client-specific molecule development.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry and drug discovery projects.

Basic Information

Product Name	Ethyl 1H-Pyrazolo[3,4-D]Pyrimidine-6-Carboxylate
CAS No.	2106690-78-0
Molecular Formula	C9H8N4O2
Molecular Weight	204.19 g/mol
Synonyms	Ethyl 1H-Pyrazolo[3,4-d]pyrimidine-6-carboxylate; 1H-Pyrazolo[3,4-d]pyrimidine-6-carboxylic acid, ethyl ester; Ethyl pyrazolopyrimidine-6-carboxylate; 6-(Ethoxycarbonyl)-1H-pyrazolo[3,4-d]pyrimidine; CAS 2106690-78-0
EINECS	Contact for details

Quality Control

Our Ethyl 1H-Pyrazolo[3,4-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.