Description

1-(Pyrimidin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical intermediate in modern drug discovery and development. Its value lies in its role as a versatile building block for synthesizing novel bioactive molecules, particularly in medicinal chemistry programs. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and the development of novel therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Chemical Biology: Serves as a precursor for designing molecular probes and tool compounds to study biological pathways.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations requiring reliable, scalable intermediates for custom synthesis projects.

Basic Information

Product Name	1-(Pyrimidin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride
CAS No.	2098048-53-2
Molecular Formula	C8H13N5 · 2HCl
Molecular Weight	268.14 g/mol (free base: 179.22 g/mol)
Synonyms	3-Amino-1-(2-pyrimidinyl)pyrrolidine dihydrochloride; 1-(Pyrimidin-2-yl)pyrrolidin-3-amine hydrochloride (1:2); Pyrrolidin-3-amine, 1-(2-pyrimidinyl)-, dihydrochloride; 2098048-53-2; 1-(2-Pyrimidinyl)-3-pyrrolidinamine dihydrochloride; 1-(Pyrimidin-2-yl)-3-aminopyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring GMP-grade intermediates and materials for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.