Description

n-(5-Iodo-4-Oxo-7-Tosyl-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Pivalamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold or precursor in the development of novel kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes to improve drug potency and selectivity.
• Bioconjugation & Probe Development: The iodine moiety provides a handle for further functionalization, useful in creating chemical probes for biological target identification.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Item	Details
Product Name	n-(5-Iodo-4-Oxo-7-Tosyl-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Pivalamide
CAS No.	2097938-60-6
Molecular Formula	C18H19IN4O4S
Molecular Weight	530.33 g/mol
Synonyms	Pivalamide, N-[5-iodo-4-oxo-7-[(4-methylphenyl)sulfonyl]-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-2-yl]-; 2-Pivalamido-5-iodo-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-one; 5-Iodo-2-(pivalamido)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one; 2097938-60-6; N-(5-Iodo-4-oxo-7-tosyl-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)pivalamide
EINECS	Contact for details

Quality Control

Our n-(5-Iodo-4-Oxo-7-Tosyl-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Pivalamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.