Description

1H-Benzimidazole-6-Carboxylic Acid, 2-[1-(5-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-4-Piperidinyl]-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists working on targeted kinase inhibitors, particularly in oncology and inflammatory disease research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable supply of complex heterocyclic building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Preclinical Development: Serves as a critical precursor for producing Active Pharmaceutical Ingredients (APIs) in small-scale GMP campaigns.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying specific biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Item	Detail
Product Name	1H-Benzimidazole-6-Carboxylic Acid, 2-[1-(5-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-4-Piperidinyl]-, Methyl Ester
CAS No.	2097938-51-5
Molecular Formula	C20H19ClN6O2
Molecular Weight	410.86 g/mol
Synonyms	Methyl 2-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]-1H-benzimidazole-6-carboxylate; 2-[1-(5-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinyl]-1H-benzimidazole-6-carboxylic acid methyl ester; 2097938-51-5; UNII-4Q7J4J8G6F; 4Q7J4J8G6F; AKOS040757625; F2198-1724; SCHEMBL23309977; DTXSID701126935
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazole-6-Carboxylic Acid, 2-[1-(5-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-4-Piperidinyl]-, Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research applications. All materials are supported by comprehensive analytical data, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.