Description

3-Bromo-Pyrrolo[1,2-A]Pyrimidine-6-Carboxylic Acid Ethyl Ester is a high-value brominated heterocyclic building block critical for advanced organic synthesis. This compound matters as a versatile intermediate, enabling the construction of complex molecular architectures through cross-coupling and functional group transformations. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically relevant scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced active ingredients for crop protection products.
• Chemical Research & Development: Serves as a versatile building block for constructing complex pyrrolopyrimidine derivatives in academic and industrial labs.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and specialty polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions.
• Library Synthesis: Employed in parallel and combinatorial chemistry for generating diverse compound libraries for biological screening.

Basic Information

Product Name	3-Bromo-Pyrrolo[1,2-A]Pyrimidine-6-Carboxylic Acid Ethyl Ester
CAS No.	2097068-59-0
Molecular Formula	C11H10BrN3O2
Molecular Weight	296.12 g/mol
Synonyms	Ethyl 3-Bromopyrrolo[1,2-a]pyrimidine-6-carboxylate; 3-Bromo-6-(ethoxycarbonyl)pyrrolo[1,2-a]pyrimidine; 3-Bromopyrrolo[1,2-a]pyrimidine-6-carboxylic Acid Ethyl Ester; Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 3-bromo-, ethyl ester; 2097068-59-0; 3-Bromo-6-carbethoxypyrrolo[1,2-a]pyrimidine; Ethyl 3-bromo-6-pyrrolo[1,2-a]pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Our 3-Bromo-Pyrrolo[1,2-A]Pyrimidine-6-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.