Description

5-Bromo-3-Fluoro-2-Iodoaniline is a highly functionalized aniline derivative, serving as a critical multi-halogenated building block in advanced organic synthesis. Its value lies in providing three distinct halogen handles (Br, F, I) for selective cross-coupling and functional group transformations, enabling the rapid construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: An invaluable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis via parallel and combinatorial chemistry.
• Ligand and Catalyst Preparation: Employed in the synthesis of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry: The presence of a fluorine atom makes it a valuable substrate for studying fluorine-specific reactions and incorporating fluorinated motifs into target molecules.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-Iodoaniline
CAS No.	2092868-81-8
Molecular Formula	C6H4BrFIN
Molecular Weight	315.91 g/mol
Synonyms	2-Iodo-5-bromo-3-fluoroaniline; 3-Fluoro-5-bromo-2-iodoaniline; Benzenamine, 5-bromo-3-fluoro-2-iodo-; 5-Bromo-3-fluoro-2-iodobenzenamine; 2-Amino-4-bromo-6-fluoroiodobenzene; 4-Bromo-2-fluoro-6-iodoaniline
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoro-2-Iodoaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.