Description

2-Fluoro-5-Iodo-4-Methoxy-Phenylamine is a high-purity, multi-functional aromatic amine building block of significant interest in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the fluorine and iodine substituents for bioactivity and metabolic stability.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis, enabling challenging cross-coupling and C-H activation reactions.
• Material Science: A monomer or functionalization agent in the synthesis of advanced polymers, liquid crystals, and organic electronic materials (e.g., OLEDs).
• Chemical Biology & Proteomics: Employed as a probe or linker in bioconjugation chemistry and the development of chemical tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated aniline derivatives.

Basic Information

Product Name	2-Fluoro-5-Iodo-4-Methoxy-Phenylamine
CAS No.	2092595-26-9
Molecular Formula	C7H7FINO
Molecular Weight	267.04 g/mol
Synonyms	4-Methoxy-2-fluoro-5-iodoaniline; 5-Iodo-2-fluoro-4-methoxyaniline; 2-Fluoro-4-methoxy-5-iodoaniline; 2-Fluoro-5-iodo-4-methoxybenzenamine; 1-Amino-2-fluoro-5-iodo-4-methoxybenzene; Benzenamine, 2-fluoro-5-iodo-4-methoxy-; 5-Iodo-4-methoxy-2-fluoroaniline
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodo-4-Methoxy-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.