Description

Benzenamine, 2-(Difluoromethyl)-3-Fluoro- is a fluorinated aniline derivative, a high-value building block in advanced organic synthesis. Its unique difluoromethyl and fluoro substituents on the aromatic ring make it a critical intermediate for introducing specific fluorine motifs, which are essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Benzenamine, 2-(Difluoromethyl)-3-Fluoro-
CAS No.	2091605-37-5
Molecular Formula	C7H6F3N
Molecular Weight	161.12 g/mol
Synonyms	2-(Difluoromethyl)-3-fluoroaniline; 3-Fluoro-2-(difluoromethyl)aniline; 2-(Difluoromethyl)-3-fluorobenzenamine; 1-Amino-2-(difluoromethyl)-3-fluorobenzene; 3-Fluoro-2-(difluoromethyl)benzenamine; (2-(Difluoromethyl)-3-fluorophenyl)amine
EINECS	Contact for details

Quality Control

Our Benzenamine, 2-(Difluoromethyl)-3-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications in GMP and ISO 9001 environments, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.