Description

4-Difluoromethoxy-2,6-Dimethylbenzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoromethoxy and aldehyde functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the difluoromethoxy group for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with specific optical or electronic properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory and R&D laboratories.

Basic Information

Product Name	4-Difluoromethoxy-2,6-Dimethylbenzaldehyde
CAS No.	2091583-03-6
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2,6-Dimethyl-4-(difluoromethoxy)benzaldehyde; 4-(Difluoromethoxy)-2,6-dimethylbenzaldehyde; Benzaldehyde, 4-(difluoromethoxy)-2,6-dimethyl-; DFMB Aldehyde; 2,6-Dimethyl-4-difluoromethoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Difluoromethoxy-2,6-Dimethylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.