Description

(R)-3-(2-Chloro-6-Methyl-4-Pyrimidinyl)-4-Isopropyl-2-Oxazolidinone CAS NO 2089381-65-5 is a high-purity, chiral oxazolidinone derivative that serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. Its value lies in its defined stereochemistry and functionalized heterocyclic structure, enabling the precise construction of complex molecules with targeted biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly those developing novel active ingredients requiring a specific chiral center.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block to induce stereoselectivity in complex organic transformations, such as aldol reactions and alkylations.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and fungicides with improved efficacy and environmental profiles.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive compounds.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for chiral target molecules.
• Fine Chemical Synthesis: A valuable reagent for the custom synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Item	Details
Product Name	(R)-3-(2-Chloro-6-Methyl-4-Pyrimidinyl)-4-Isopropyl-2-Oxazolidinone
CAS No.	2089381-65-5
Molecular Formula	C11H14ClN3O2
Molecular Weight	255.70 g/mol
Synonyms	(R)-4-Isopropyl-3-(2-chloro-6-methylpyrimidin-4-yl)oxazolidin-2-one; (R)-Enantiomer of 3-(2-Chloro-6-methyl-4-pyrimidinyl)-4-isopropyl-2-oxazolidinone; UNII-7R8F4CJ39Q; (R)-Oxazolidinone derivative; Chiral oxazolidinone auxiliary; (R)-IPCO; (2R)-3-(2-Chloro-6-methyl-4-pyrimidinyl)-4-(1-methylethyl)-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-3-(2-Chloro-6-Methyl-4-Pyrimidinyl)-4-Isopropyl-2-Oxazolidinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity (enantiomeric excess), to ensure it meets the high standards required for pharmaceutical R&D and production. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.