Description

Pyrimidine, 5-Chloro-2-(Methylthio)-4-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and chloromethylthio substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and bioactive compounds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in antiviral, anticancer, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystal displays (LCDs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Pyrimidine, 5-Chloro-2-(Methylthio)-4-(Trifluoromethyl)-
CAS No.	2089334-51-8
Molecular Formula	C7H4ClF3N2S
Molecular Weight	240.63 g/mol
Synonyms	5-Chloro-2-(methylthio)-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-5-chloro-2-(methylthio)pyrimidine; 2-Methylthio-5-chloro-4-trifluoromethylpyrimidine; 5-Chloro-4-(trifluoromethyl)-2-(methylsulfanyl)pyrimidine; 5-Chloro-2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine; CAS 2089334-51-8
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 5-Chloro-2-(Methylthio)-4-(Trifluoromethyl)- is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and GC-MS analyses. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.