Description

5-Bromo-2-Methoxy-4-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring bromine, methoxy, and trifluoromethyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core and halogen/CF3 groups.
• Material Science: Building block for creating specialty polymers, liquid crystals, and electronic materials where the trifluoromethyl group imparts specific stability and electronic properties.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions in medicinal and process chemistry.
• R&D Reference Standard: Serves as a pure analytical standard for method development and quality control in laboratories.

Basic Information

Product Name	5-Bromo-2-Methoxy-4-(Trifluoromethyl)Pyrimidine
CAS No.	2089333-61-7
Molecular Formula	C6H4BrF3N2O
Molecular Weight	257.01 g/mol
Synonyms	5-Bromo-2-methoxy-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-5-bromo-2-methoxypyrimidine; 2-Methoxy-5-bromo-4-(trifluoromethyl)pyrimidine; 5-Bromo-4-(trifluoromethyl)-2-methoxypyrimidine; Pyrimidine, 5-bromo-2-methoxy-4-(trifluoromethyl)-; 2089333-61-7
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxy-4-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures a reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.