Description

Pyrido[3,4-D]Pyrimidin-4(3H)-One, 6-Fluoro-2-Methyl- is a high-purity, fluorinated pyridopyrimidinone derivative, a privileged scaffold in modern medicinal chemistry. This compound is critical for pharmaceutical research and development, serving as a key building block for the synthesis of novel kinase inhibitors and targeted therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of small molecule kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Probe: Used to study enzyme function and signal transduction pathways in academic and industrial research settings.
• Agrochemical Development: Serves as a core structure for developing new active ingredients with potential fungicidal or herbicidal properties.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening campaigns for drug discovery.
• Custom Synthesis: Used as a starting material for the custom synthesis of more complex, target-specific molecules under cGMP or non-GMP conditions.

Basic Information

Product Name	Pyrido[3,4-D]Pyrimidin-4(3H)-One, 6-Fluoro-2-Methyl-
CAS No.	2089325-37-9
Molecular Formula	C8H6FN3O
Molecular Weight	179.15 g/mol
Synonyms	6-Fluoro-2-methyl-3H-pyrido[3,4-d]pyrimidin-4-one; 6-Fluoro-2-methylpyrido[3,4-d]pyrimidin-4(3H)-one; 6-Fluoro-2-methyl-4(3H)-pyrido[3,4-d]pyrimidinone; 2089325-37-9; 6-Fluoro-2-methyl-3,4-dihydropyrido[3,4-d]pyrimidin-4-one; Fluorinated pyridopyrimidinone; 2-Methyl-6-fluoropyrido[3,4-d]pyrimidin-4-ol (tautomer)
EINECS	Contact for details

Quality Control

Our Pyrido[3,4-D]Pyrimidin-4(3H)-One, 6-Fluoro-2-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.