Description

Methyl 2-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-4-Carboxylate is a high-value heterocyclic building block and key synthetic intermediate. This compound is critical for research and development in medicinal chemistry, enabling the construction of novel pharmacologically active scaffolds. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted small molecule libraries and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing novel compound libraries in drug discovery programs.
• Chemical Biology Probes: Used in the development of tool compounds for studying biological pathways and target validation.
• Agrochemical Synthesis: Potential intermediate in the research and development of new crop protection agents.
• Academic & Contract Research: Essential for synthetic organic chemistry research in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	Methyl 2-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-4-Carboxylate
CAS No.	2089277-65-4
Molecular Formula	C8H6ClN3O2
Molecular Weight	211.60 g/mol
Synonyms	2-Chloro-5H-pyrrolo[3,2-d]pyrimidine-4-carboxylic acid methyl ester; Methyl 2-chloro-5H-pyrrolo[3,2-d]pyrimidine-4-carboxylate; 4-Carbomethoxy-2-chloro-5H-pyrrolo[3,2-d]pyrimidine; 2-Chloro-4-(methoxycarbonyl)-5H-pyrrolo[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-4-Carboxylate adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. All materials are characterized by modern analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.