Description

(2S,3R)-3-(3,4-Difluorophenyl)-2-(4-Fluorophenyl)-4-Hydroxy-n-((3S)-2-Oxo-5-Phenyl-2,3-1H-Benzo[E][1,4]Diazepin-3-Yl)Butyramide is a high-purity, non-racemic chiral compound featuring a complex benzodiazepine core. This molecule is of significant commercial interest as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) building block in modern drug discovery. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology spaces.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of advanced drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Used as a core structural moiety for developing new benzodiazepine-derived therapeutics.
• Medicinal Chemistry & Drug Discovery: A valuable compound for structure-activity relationship (SAR) studies and lead optimization in preclinical research.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays to study receptor interactions and enzyme inhibition.
• Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Custom Synthesis Building Block: Provides a sophisticated starting point for contract research organizations (CROs) and CDMOs performing custom synthesis projects.

Basic Information

Product Name	(2S,3R)-3-(3,4-Difluorophenyl)-2-(4-Fluorophenyl)-4-Hydroxy-n-((3S)-2-Oxo-5-Phenyl-2,3-1H-Benzo[E][1,4]Diazepin-3-Yl)Butyramide
CAS No.	2081093-21-0
Molecular Formula	C31H22F3N3O3
Molecular Weight	541.52 g/mol
Synonyms	(2S,3R)-3-(3,4-Difluorophenyl)-2-(4-fluorophenyl)-4-hydroxy-N-[(3S)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]butyramide; (2S,3R)-3-(3,4-Difluorophenyl)-2-(4-Fluorophenyl)-4-Hydroxy-n-((3S)-2-Oxo-5-Phenyl-2,3-Dihydro-1H-Benzo[E][1,4]Diazepin-3-Yl)Butyramide; Benzodiazepine Derivative CAS 2081093-21-0; Chiral Benzodiazepine Amide; Trifluorinated Benzodiazepine Intermediate; 2081093-21-0; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (2S,3R)-3-(3,4-Difluorophenyl)-2-(4-Fluorophenyl)-4-Hydroxy-n-((3S)-2-Oxo-5-Phenyl-2,3-1H-Benzo[E][1,4]Diazepin-3-Yl)Butyramide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and kept in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.