Description

4-Chloro-2-Iodo-5-Trifluoromethyl-Phenol is a halogenated phenol derivative with a unique trifluoromethyl substituent, making it a versatile and valuable synthetic intermediate. This compound is particularly significant for its role in the development of advanced materials and active pharmaceutical ingredients (APIs), where its distinct substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the bioactivity of halogenated phenols.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores essential in electronic display technologies.
• Polymer Modification Agent: Employed to introduce halogen and trifluoromethyl groups into polymer chains to alter thermal stability, solubility, and chemical resistance.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile palladium-catalyzed coupling reactions (e.g., Suzuki, Sonogashira) in complex molecule assembly.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorinated compounds and their properties.

Basic Information

Product Name	4-Chloro-2-Iodo-5-Trifluoromethyl-Phenol
CAS No.	2065250-62-4
Molecular Formula	C7H3ClF3IO
Molecular Weight	321.45 g/mol
Synonyms	2-Iodo-4-chloro-5-(trifluoromethyl)phenol; 4-Chloro-2-iodo-α,α,α-trifluoro-m-cresol; 5-Trifluoromethyl-4-chloro-2-iodophenol; Phenol, 4-chloro-2-iodo-5-(trifluoromethyl)-; 4-Chloro-2-iodo-5-(trifluoromethyl)phenol; 2-Iodo-4-chloro-α,α,α-trifluoro-m-cresol
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Iodo-5-Trifluoromethyl-Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specification results. We support compliance with relevant regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.