Description

3-(Aminomethyl)-5-Fluorophenol Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is valued for its bifunctional structure, featuring both a phenolic hydroxyl group and a primary amine hydrochloride, which enables its use in sophisticated synthetic pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring fluorinated phenolic structures.
• Chemical Research & Development: Serves as a versatile building block for constructing complex molecules in medicinal and organic chemistry.
• Ligand and Chelator Precursor: The amine and phenol functional groups make it suitable for synthesizing ligands for catalysis or metal chelation.
• Material Science: Potential use in the synthesis of specialty polymers and advanced materials where fluorinated monomers are required.
• Bioconjugation Chemistry: The reactive amine group (as HCl salt) can be utilized for coupling reactions in probe and linker synthesis.

Basic Information

Product Name	3-(Aminomethyl)-5-Fluorophenol Hydrochloride
CAS No.	2061979-49-3
Molecular Formula	C7H9ClFNO
Molecular Weight	177.60 g/mol
Synonyms	5-Fluoro-3-(aminomethyl)phenol hydrochloride; 3-(Aminomethyl)-5-fluorophenol HCl; 5-Fluoro-3-(aminomethyl)phenol HCl; (3-Hydroxy-5-fluorophenyl)methanamine hydrochloride; Benzenemethanamine, 3-hydroxy-5-fluoro-, hydrochloride; 5-Fluoro-3-hydroxybenzylamine hydrochloride; 3-Hydroxy-5-fluorobenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Aminomethyl)-5-Fluorophenol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.