Description

3-Bromo-2,4,5-Trifluoroaniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions) to introduce complex aniline motifs.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	3-Bromo-2,4,5-Trifluoroaniline
CAS No.	2055841-42-2
Molecular Formula	C6H2BrF3N
Molecular Weight	225.99 g/mol
Synonyms	2,4,5-Trifluoro-3-bromoaniline; 3-Bromo-2,4,5-trifluorobenzenamine; 1-Amino-3-bromo-2,4,5-trifluorobenzene; Benzenamine, 3-bromo-2,4,5-trifluoro-; 3-Br-2,4,5-F3-C6H2NH2; 3-Bromo-2,4,5-trifluoro-phenylamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4,5-Trifluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.