Description

1-(5-Bromopyrimidin-2-Yl)Cyclopropan-1-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyrimidine core fused with a cyclopropylamine moiety. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing targeted therapies, particularly in oncology and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic and bioorganic chemistry.

Basic Information

Product Name	1-(5-Bromopyrimidin-2-Yl)Cyclopropan-1-Amine Hydrochloride
CAS No.	2055841-13-7
Molecular Formula	C7H9BrClN3
Molecular Weight	250.52 g/mol
Synonyms	1-(5-Bromopyrimidin-2-yl)cyclopropanamine hydrochloride; 1-(5-Bromo-2-pyrimidinyl)cyclopropanamine hydrochloride; Cyclopropanamine, 1-(5-bromo-2-pyrimidinyl)-, hydrochloride (1:1); 1-(5-Bromopyrimidin-2-yl)cyclopropan-1-amine HCl; 1-(5-Bromo-pyrimidin-2-yl)-cyclopropylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyrimidin-2-Yl)Cyclopropan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.