Description

2-Fluoro-3-Methyl-5-(Trifluoromethyl)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as metabolic stability and enhanced lipophilicity to target molecules. This compound is critically needed by R&D and process development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the fluorine motifs improve biological activity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials requiring specific dipole moments and stability.
• Advanced Polymer Modification: Incorporates into specialty polymer backbones to alter thermal, chemical, and surface properties.
• Cross-Coupling Reactions: The aldehyde group is readily transformed, making it a versatile substrate for Suzuki, Sonogashira, and other metal-catalyzed couplings.
• Fluorine Chemistry Research: An important standard and reagent for studying structure-activity relationships (SAR) in fluorinated compound libraries.

Basic Information

Product Name	2-Fluoro-3-Methyl-5-(Trifluoromethyl)Benzaldehyde
CAS No.	2055275-09-5
Molecular Formula	C9H6F4O
Molecular Weight	206.14 g/mol
Synonyms	5-(Trifluoromethyl)-2-fluoro-3-methylbenzaldehyde; 3-Methyl-2-fluoro-5-(trifluoromethyl)benzaldehyde; 2-Fluoro-3-methyl-5-trifluoromethylbenzaldehyde; Benzaldehyde, 2-fluoro-3-methyl-5-(trifluoromethyl)-; α,α,α-Trifluoro-5-formyl-2-fluoro-3-methyltoluene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methyl-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent oxidation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.