Description

3-(2-Chloropyrimidine-5-Carbonyl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-carbonitrile scaffold. This compound matters for its critical role as a versatile building block in the synthesis of complex, biologically active molecules, enabling the development of new therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides and fungicides leveraging its heterocyclic structure.
• Chemical Biology: Serves as a valuable probe or linker in the design of chemical tools for studying biological pathways.
• Material Science: Potential monomer or additive for creating specialized polymers with specific electronic or binding properties.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Product Name	3-(2-Chloropyrimidine-5-Carbonyl)Benzonitrile
CAS No.	2054952-83-7
Molecular Formula	C12H6ClN3O
Molecular Weight	243.65 g/mol
Synonyms	2-Chloro-5-(3-cyanobenzoyl)pyrimidine; 3-[(2-Chloropyrimidin-5-yl)carbonyl]benzonitrile; Benzonitrile, 3-[(2-chloro-5-pyrimidinyl)carbonyl]-; 2054952-83-7; 3-(2-Chloro-pyrimidine-5-carbonyl)-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-(2-Chloropyrimidine-5-Carbonyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.