Description

Boc-n-Me-Glu-Oh CAS NO 2044711-06-8 is a protected amino acid derivative, specifically N-Boc-N-methyl-L-glutamic acid, serving as a critical chiral building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the construction of complex peptide and peptidomimetic structures. It is primarily utilized in pharmaceutical R&D for the synthesis of active pharmaceutical ingredients (APIs), novel drug candidates, and in the development of specialized biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs and complex bioactive molecules.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a protected glutamic acid residue with an N-methylated backbone.
• Protease Inhibitor Development: Serves as a core component in the design and synthesis of enzyme inhibitors targeting proteases.
• Chemical Biology Research: Employed in the preparation of labeled peptides, molecular probes, and tools for studying protein-protein interactions.
• Combinatorial Chemistry: A valuable building block for creating diverse chemical libraries in drug discovery programs.
• Agrochemical Synthesis: Potential intermediate in the development of specialized, chiral agrochemicals.

Basic Information

Product Name	Boc-n-Me-Glu-Oh
CAS No.	2044711-06-8
Molecular Formula	C11H19NO6
Molecular Weight	261.27 g/mol
Synonyms	N-Boc-N-methyl-L-glutamic acid; (S)-2-((tert-Butoxycarbonyl)(methyl)amino)pentanedioic acid; Boc-N-Me-L-Glu-OH; N-α-Boc-N-α-methyl-L-glutamic acid; tert-Butyl (1S)-4-carboxy-1-(methoxycarbonyl)butyl(methyl)carbamate; Boc-N-methylglutamic acid; N-Methyl-N-Boc-L-glutamic acid
EINECS	Contact for details

Quality Control

Our Boc-n-Me-Glu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and NMR for structural confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.