Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Trp(Boc)-Oh is a sophisticated, protected amino acid derivative specifically engineered for advanced peptide synthesis. This compound matters as a critical building block for pharmaceutical research, enabling the precise construction of complex peptides with enhanced metabolic stability and targeted bioactivity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel therapeutic peptides, peptidomimetics, and proteomics research.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected, side-chain protected intermediate for the sequential assembly of peptide chains.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based therapeutics, including hormone analogs and receptor-targeting drugs.
• Peptidomimetic Design: Incorporation of the N-methyl-D-tryptophan residue is valuable for creating peptidomimetics with improved bioavailability and resistance to enzymatic degradation.
• Process Chemistry: Employed in the scale-up and optimization of peptide active pharmaceutical ingredient (API) manufacturing processes.
• Bioconjugation: Can be used to create peptide tags or linkers for protein labeling and bioconjugation strategies.
• Academic Research: A vital reagent for university and institutional labs studying peptide structure-activity relationships (SAR) and chemical biology.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Trp(Boc)-Oh
CAS No.	2044709-90-0
Molecular Formula	C34H36N2O6
Molecular Weight	568.66 g/mol
Synonyms	Fmoc-N-Me-D-Trp(Boc)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-tryptophan N-tert-butoxycarbonyl; Fmoc-N-methyl-D-tryptophan(Boc)-OH; Nα-Fmoc-Nin-Boc-N-methyl-D-tryptophan; Fmoc-N-Me-D-Trp(Boc)-OH; Nα-(9-Fluorenylmethoxycarbonyl)-Nin-(tert-butoxycarbonyl)-N-methyl-D-tryptophan; (2R)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]-2-methylpropanoic acid
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Trp(Boc)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, and is supplied with a comprehensive Certificate of Analysis (COA). We adhere to high-purity standards suitable for pharmaceutical R&D, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.