Description

2-(4-(Azetidin-3-Yl)Piperazin-1-Yl)Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new drug candidates targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and GPCR-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile piperazine-pyrimidine core.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Preclinical Development: Employed in the scale-up synthesis of active pharmaceutical ingredients (APIs) for toxicology and early-phase clinical studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Library Synthesis: Used in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-(4-(Azetidin-3-Yl)Piperazin-1-Yl)Pyrimidine Hydrochloride
CAS No.	2044704-96-1
Molecular Formula	C11H18ClN5
Molecular Weight	255.75 g/mol
Synonyms	2-[4-(Azetidin-3-yl)piperazin-1-yl]pyrimidine hydrochloride; 2-(4-(Azetidin-3-yl)piperazin-1-yl)pyrimidine HCl; 2-(4-(3-Azetidinyl)-1-piperazinyl)pyrimidine hydrochloride; 2044704-96-1; Azetidin-3-yl-piperazinyl-pyrimidine hydrochloride; Pyrimidine, 2-[4-(3-azetidinyl)-1-piperazinyl]-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-(Azetidin-3-Yl)Piperazin-1-Yl)Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.