Description

Fmoc-Alg(Me,Pbf)-Oh CAS NO 2044702-31-8 is a protected amino acid derivative, specifically an Fmoc-protected arginine analog with side-chain protecting groups, essential for solid-phase peptide synthesis (SPPS). This high-purity building block is critical for ensuring the fidelity and efficiency of complex peptide chain assembly, particularly for sequences containing arginine. It is primarily used by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of therapeutic peptides, diagnostic reagents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated or manual synthesis of custom peptides.
• Pharmaceutical Research & Development: For the discovery and production of novel peptide-based drug candidates, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation & Probe Development: Serving as a modified arginine residue in the synthesis of labeled peptides for imaging, diagnostic assays, and target identification.
• Academic & Institutional Research: Used in biochemistry and molecular biology laboratories for studying protein-protein interactions, enzyme substrates, and signal transduction pathways.
• Production of Peptide Libraries: Enabling combinatorial chemistry approaches for high-throughput screening in drug discovery platforms.
• Synthesis of Biologically Active Peptides: For creating peptides with specific biological activities used in cosmetic (e.g., anti-aging peptides) and nutraceutical applications.

Basic Information

Product Name	Fmoc-Alg(Me,Pbf)-Oh
CAS No.	2044702-31-8
Molecular Formula	C₃₃H₄₅N₅O₈S
Molecular Weight	671.81 g/mol
Synonyms	Fmoc-Arg(Pbf)-OH; N-α-Fmoc-N-ω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine; Fmoc-L-arginine(Pbf)-OH; Fmoc-Arg(Pbf)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-ω-[(2,2,4,6,7-pentamethyldihydrobenzofuran-5-yl)sulfonyl]-L-arginine; Fmoc-Arg(Pbf)-OH (Fmoc-L-Arg(Pbf)-OH); Fmoc-Arg(Pbf)-OH (Fmoc-L-Arg(Pbf)-OH) CAS 154445-77-9 (base structure); Fmoc-Arg(Pbf)-OH derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Alg(Me,Pbf)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive peptide synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.