Description

n-((3R,6S)-6-Methylpiperidin-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of novel kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Assay Development: Serves as a reference standard or probe molecule in high-throughput screening (HTS) assays.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for studying purine/pyrimidine-based signaling pathways.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial chemical entities.

Basic Information

Product Name	n-((3R,6S)-6-Methylpiperidin-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No.	2042650-70-2
Molecular Formula	C12H17N5
Molecular Weight	231.30 g/mol
Synonyms	4-Amino-7H-pyrrolo[2,3-d]pyrimidine, N-[(3R,6S)-6-methyl-3-piperidinyl]-; (3R,6S)-N-(6-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-[(3R,6S)-6-methyl-3-piperidinyl]-; 2042650-70-2; (3R,6S)-6-Methyl-N-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-amine
EINECS	Contact for details

Quality Control

Our n-((3R,6S)-6-Methylpiperidin-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade and cGMP standards for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, NMR) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated area. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.