Description

6-Chloropyrazolo[1,5-A]Pyrimidine is a high-purity heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrazolopyrimidine scaffold enables the creation of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a versatile scaffold for constructing molecular probes and tool compounds in biochemical research.
• Material Science: Potential building block for advanced organic electronic materials and functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up.

Basic Information

Product Name	6-Chloropyrazolo[1,5-A]Pyrimidine
CAS No.	2024538-64-3
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	6-Chloro-1H-pyrazolo[1,5-a]pyrimidine; 6-Chloropyrazolo[1,5-a]pyrimidine; 6-Chloro-1H-pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 6-chloro-; 2024538-64-3
EINECS	Contact for details

Quality Control

Our 6-Chloropyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. We support development and commercial projects with specifications that can meet the stringent requirements of cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.