Description

(β-D-Asp28)-Exenatide CAS NO 2022976-04-9 is a synthetic, modified peptide analog of exendin-4, engineered for enhanced stability and therapeutic potential. This compound is of significant interest for its role in advanced pharmaceutical research and development, particularly in the study of metabolic disorders. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and academic research institutions focused on endocrinology and drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel therapeutics for Type 2 diabetes and obesity.
• GLP-1 Receptor Agonist Studies: Used in preclinical and clinical research to investigate the mechanisms and efficacy of glucagon-like peptide-1 (GLP-1) receptor activation.
• Metabolic Disorder Research: A critical tool for studying insulin secretion, glucose homeostasis, and appetite regulation in experimental models.
• Peptide Chemistry & Formulation: Employed in the development of stable peptide formulations, delivery systems, and long-acting injectables.
• Quality Control & Analytical Testing: Functions as a high-purity certified reference material (CRM) for method validation, assay calibration, and impurity profiling in QC laboratories.
• Academic & Institutional Research: Supports fundamental scientific studies in biochemistry, pharmacology, and molecular biology related to incretin hormones.

Basic Information

Product Name	(β-D-Asp28)-Exenatide
CAS No.	2022976-04-9
Molecular Formula	C184H282N50O60S
Molecular Weight	4186.6 g/mol
Synonyms	Exenatide (β-D-Asp28) analog; (D-Asp28)-Exendin-4; LY2148568; ITCA 650; Exenatide LAR; GLP-1 agonist analog; Synthetic exendin-4 derivative; Bydureon® (related branded product)
EINECS	Contact for details

Quality Control

Our (β-D-Asp28)-Exenatide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and potency. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	≤ 15.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.