Description

Biotinyl-εahx-Ll-37 (Scrambled) is a synthetic, biotinylated derivative of the scrambled sequence of the human antimicrobial peptide LL-37, designed for advanced biochemical research. This modified peptide is a critical tool for studying protein-protein interactions, cellular uptake mechanisms, and signal transduction pathways via streptavidin-biotin affinity systems. It is primarily utilized by researchers and developers in the fields of pharmaceutical R&D, proteomics, and immunology for applications ranging from target identification to diagnostic assay development.

Application

• Biochemical Research & Assay Development: Used as a tagged ligand in pull-down assays, ELISA, and Western blotting to investigate binding partners and signaling cascades.
• Drug Discovery Platforms: Serves as a key component in high-throughput screening (HTS) systems for identifying novel antimicrobial or immunomodulatory compounds.
• Diagnostic Probe Synthesis: Employed in the development of sensitive detection kits and biosensors due to the high-affinity biotin-streptavidin interaction.
• Cell Biology Studies: Facilitates the study of peptide internalization, localization, and function within cellular models using fluorescence or other detection methods.
• Material Science & Bioconjugation: Acts as a versatile building block for creating functionalized surfaces, nanoparticles, or biomaterials for targeted delivery systems.

Basic Information

Product Name	Biotinyl-εahx-Ll-37 (Scrambled)
CAS No.	2022972-72-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-LL-37 (Scrambled); Biotinylated LL-37 Scrambled Control Peptide; Biotin-Ahx-LL-37 (Scrambled); Biotin-6-Aminohexanoic acid-LL-37 Scrambled; Scrambled LL-37 Biotin Conjugate; hCAP-18 (Scrambled) Biotin Labeled; Antimicrobial Peptide LL-37 Scrambled Biotin Tag; Cathelicidin LL-37 (Scrambled) Biotinylated
EINECS	Contact for details

Quality Control

Every batch of Biotinyl-εahx-Ll-37 (Scrambled) is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with rigorous standards for research-grade peptides, including identity confirmation and purity verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as purity, molecular weight, and peptide content.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Molecular Weight (MS)	Conforms to theoretical value
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.