Description

H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Tyr-Arg-Ser-Pro-Ala-Ser-Met-Pro-Glu-Asn-Leu-Oh is a synthetic, high-purity peptide sequence of significant interest in advanced biochemical research and development. This compound is valued for its specific amino acid arrangement, which makes it a crucial tool for studying protein-protein interactions, signal transduction pathways, and as a potential precursor in pharmaceutical discovery. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers engaged in proteomics, peptide therapeutics, and molecular biology. Consistent quality and reliable supply are paramount for these critical applications.

Application

• Biochemical Research: Serves as a key reference standard or active component in studies of cell signaling, enzyme kinetics, and receptor-ligand binding assays.
• Pharmaceutical R&D: Investigated as a potential lead compound or intermediate in the development of novel peptide-based therapeutics targeting specific biological pathways.
• Proteomics & Genomics: Used in mass spectrometry calibration, antibody production, and as a model peptide in structural biology studies to understand protein folding and function.
• Diagnostic Development: May be employed in the design and validation of diagnostic kits and assays that require specific peptide antigens or probes.
• Academic Research: A vital reagent for university and institutional labs conducting fundamental research in biochemistry, molecular biology, and medicinal chemistry.
• Peptide Library Synthesis: Acts as a complex building block or a control sequence in the synthesis and screening of combinatorial peptide libraries for drug discovery.

Basic Information

Product Name	H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Tyr-Arg-Ser-Pro-Ala-Ser-Met-Pro-Glu-Asn-Leu-Oh
CAS No.	2022956-42-7
Molecular Formula	C₁₁₈H₂₁₀N₅₀O₃₀S
Molecular Weight	~2745.3 g/mol
Synonyms	Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Tyr-Arg-Ser-Pro-Ala-Ser-Met-Pro-Glu-Asn-Leu; YGRKKRRQRRRRLYRSPSM-PENL (Single-letter code); H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Tyr-Arg-Ser-Pro-Ala-Ser-Met-Pro-Glu-Asn-Leu-OH; TAT (48-60) Peptide; TAT Peptide Fragment; Cell-Penetrating Peptide (CPP) Sequence; HIV-1 TAT Protein (48-60); GRKKRRQRRRPPQ Peptide (common variant reference)
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Tyr-Arg-Ser-Pro-Ala-Ser-Met-Pro-Glu-Asn-Leu-Oh undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are provided and available upon request to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.