Description

(R)-2-Amino-3-((tert-Butoxycarbonyl)Amino)-3-Methylbutanoic Acid (Wxc05451) is a high-purity, non-natural amino acid derivative featuring a chiral center and a Boc-protected amine group. This compound serves as a critical chiral building block for the synthesis of complex peptides and peptidomimetics, enabling precise control over stereochemistry and molecular structure. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents, including protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce sterically hindered, non-proteinogenic amino acid residues into peptide chains.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of selective enzyme inhibitors.
• Chemical Biology & Proteomics: Employed in the creation of specialized probes and tools for studying protein-protein interactions and enzyme mechanisms.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Academic & Industrial Research: A valuable reagent for medicinal chemistry programs and material science research exploring novel biomimetic polymers.

Basic Information

Product Name	(R)-2-Amino-3-((tert-Butoxycarbonyl)Amino)-3-Methylbutanoic Acid (Wxc05451)
CAS No.	2007915-76-4
Molecular Formula	C11H22N2O4
Molecular Weight	246.31 g/mol
Synonyms	Boc-D-β-tert-Butylalanine; (R)-3-((tert-Butoxycarbonyl)amino)-3-methyl-2-aminobutanoic acid; (R)-2-Amino-3-[(tert-butoxycarbonyl)amino]-3-methylbutanoic acid; D-Boc-Amino-β-tert-butyl-alanine; Boc-D-Amg-OH; (2R)-2-Amino-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-methylbutanoic acid; Wxc05451
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-3-((tert-Butoxycarbonyl)Amino)-3-Methylbutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.