Description

2,6-Dichloro-5-Fluoropyrimidine-4-Carboxamide is a high-value fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. This compound is primarily sought by pharmaceutical R&D departments, agrochemical innovators, and specialty chemical manufacturers requiring precise, high-purity intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel nucleoside analogues and other potential therapeutic agents targeting viral and oncological diseases.
• Agrochemical Research: Serves as a precursor in the development of new generation herbicides and fungicides with enhanced activity and selectivity.
• Chemical Synthesis Building Block: Used in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex heterocyclic systems.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-specific molecule development.

Basic Information

Product Name	2,6-Dichloro-5-Fluoropyrimidine-4-Carboxamide
CAS No.	2006277-92-3
Molecular Formula	C5H2Cl2FN3O
Molecular Weight	207.99 g/mol
Synonyms	5-Fluoro-2,6-dichloropyrimidine-4-carboxamide; 2,6-Dichloro-5-fluoropyrimidine-4-carboxylic acid amide; 4-Carbamoyl-2,6-dichloro-5-fluoropyrimidine; 5-Fluoro-2,6-dichloro-4-pyrimidinecarboxamide; 2006277-92-3; DC-Fluoropyrimidine Carboxamide
EINECS	Contact for details

Quality Control

Every batch of 2,6-Dichloro-5-Fluoropyrimidine-4-Carboxamide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile as determined by advanced chromatographic and spectroscopic methods (HPLC, GC, NMR, MS).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed and stored in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.