Description

Ethyl 6-Methyl-4-(4-Methylphenyl)-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate is a high-purity, synthetically valuable dihydropyrimidinone (DHPM) derivative, a privileged scaffold in medicinal chemistry. This compound is critical for research and development, serving as a versatile key intermediate for the synthesis of more complex bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Core building block for the synthesis of calcium channel blockers, antiviral agents, and anti-inflammatory drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Organic Synthesis: Serves as a precursor for creating novel heterocyclic compounds with potential biological activity.
• Agrochemical Development: Investigated as an intermediate for novel crop protection agents and herbicides.
• Academic Research: Utilized in universities and research institutes for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Ethyl 6-Methyl-4-(4-Methylphenyl)-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate
CAS No.	299949-24-9
Molecular Formula	C15H18N2O3
Molecular Weight	274.32 g/mol
Synonyms	Ethyl 4-(p-Tolyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-4-(4-methylphenyl)-2-oxo-, ethyl ester; 4-(4-Methylphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester; DHPM Derivative; Biginelli Reaction Product; Dihydropyrimidinone Ester.
EINECS	Contact for details

Quality Control

Our production of Ethyl 6-Methyl-4-(4-Methylphenyl)-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and tested against rigorous internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is moisture-sensitive; ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.